The 6th International Conference on Biology and Pathobiology of KLF/Sp Transcription Factors

Kyoto Garden Palace Hotel, Kyoto Oct 28th - 31st, 2018

Programme

Time Table (PDF)

  • DAY1 October 28 (PDF)
  • DAY2 October 29 (PDF)
  • DAY3 October 30 (PDF)
  • DAY4 October 31 (PDF)

Special Lecture (Confirmed)

Special Lecture 1
Overlapping functions of Kruppel-like factor family members in mouse embryonic stem cells
Hitoshi Niwa (Kumamoto University, Japan)
Special Lecture 2
Recent Progress in iPS Cell Research and Application
Shinya Yamanaka (Nobel laureate, Kyoto University, Japan)

Presidential Lecture

KLF5 research in cardiac physiology and cancer biology
Ryozo Nagai (Jichi Medical University, Japan)

Invited Speakers (Confirmed)

KLFs in development and differentiation 1

Session1-1
The role of KLF1/EKLF in normal and aberrant erythroid differentiation
James Bieker (Mount Sinai School of Medicine, U.S.A.)
Session1-2
The roles of KLFs in regulating T cell differentiation, trafficking and function
Stephen C. Jameson (University of Minnesota, U.S.A.)

KLFs in development and differentiation 2

Session2-1
Lineage specification during mouse preimplantation development controlled by Klf5 and FGF-ERK pathway
Takuya Azami (Shiga University of Medical Science, Japan)
Session2-2
Modelling unexpected disease phenotypes due to neomorphic and hypomorphic mutations in the DNA-binding domain of SP/KLF transcription factors using integrated genomics and mouse models
Andrew Perkins (University of Queensland, Australia)
Session2-3
KLF5 in muscle development and regeneration
Yumiko Oishi (Department of Biochemistry & Molecular Biology Nippon Medical School)

KLFs in gene regulatory network

Session3-1
Regulation of Intestinal Stem Cells by KLFs
Vincent Yang (Stony Brook University, U.S.A.)
Session3-2
KLF3 controls inflammation via the STATNFkB regulatory axis
Merlin Crossley (University of New South Wales, Australia)
Session3-3
Regulation of KLFs stability by UPS pathway
Ping Wang (Tongji University, China)

KLFs in cancer 1

Session4-1
KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress
Jonathan Katz (University of Pennsylvania, U.S.A.)
Session4-2
The role of KLF5 in breast development and carcinogenesis
Ceshi Chen (Kunming Institute of Zoology, Chinese Academy of Sciences, China)

KLFs in cancer 2

Session5-1
Drugging tumor suppressor proteins: lessons from KLFs and phosphatases
Goutham Narla (Case Western Reserve University, U.S.A.)
Session5-2
KLF4 Regulation and cancer development
Zhihua Liu (Chinese Academy of Medical Sciences and Peking Union Medical College, China)

KLFs in metabolism and aging

Session6-1
Cardiomyocyte KLF5 drives diabetic cardiomyopathy
Kostantinos Drosatos (Temple University, U.S.A.)

KLFs in cardiovascular disease 1

Session7-1
KLF5 modulates the response of different cell types within the arterial wall to injury by multiple mechanisms
Jin-kun Wen (Hebei University, China)
Session7-2
KLF4 modulates different cell function by multiple mechanisms
Bin Zheng (Hebei University, China)
Session7-3
Klf4 and 5 Regulates the Long-Lasting Neural Stem Cell Population
Seiji Hitoshi (Shiga University of Medical Science, Japan)

KLFs in cardiovascular disease 2

Session8-1
Cardiovascular functions of KLF6
Toru Suzuki (University of Leicester, U.K.)

KLFs in cardiovascular disease 3

Session9-1
KLF5 controls kidney-heart inter-organ communication
Katsuhito Fujiu (The University of Tokyo, Japan)

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